Program Cores

These cores are directed by independent and established researchers who have been highly collaborative during the past 14 years, generating 54 publications, with distinct but complementary scientific expertise and background. Thus, as one of the leading lipidomics groups in the United States, we are in a unique position to dissect the mechanisms of lipid signaling in the regulation of apoptosis, tumor growth, and metastasis and to translate these mechanistic studies to the clinic for the treatment of patients with solid tumors.


The purpose of the Lipidomics Core in the PPG is to provide intellectual and physical resources (particularly state-of-the-art mass spectrometry analysis of sphingolipids and synthetic molecular tools) to enhance understanding of the role of bioactive lipids in cancer biology with the goal to discover future therapeutics.

Core Leader: Besim Ogretmen, Ph.D.

Animal Models & Pathology

The Animal Models and Pathology Core is established to provide essential animal and pathology resource components that comprehensively support research projects utilizing animal models.

Core Leader: Shikhar Mehrotra, Ph.D.


The role of the Biostatistics Core in this program is to provide biostatistical expertise in study design, data analysis, and data management. The core is staffed by three statisticians.

Core Leader: Elizabeth Garrett-Mayer, Ph.D.


The overall goals of the Administrative Core are to provide central leadership to foster productive research interactions and a high degree of integration between projects and cores, and to manage all scientific, administrative, regulatory, and fiscal responsibilities of the program.

Core Leader: Besim Ogretmen, Ph.D.