Blood & Bone Marrow Transplants

Dr. Brian Hess, part of the Blood & Marrow Transplant Program team, seeing a patient in clinic

For more than 30 years, MUSC Hollings Cancer Center has been South Carolina's leader in blood and bone marrow transplantation and CAR-T cell therapy. We are the only Foundation for Accreditation of Cellular Therapy (FACT)-accredited combined adult and pediatric Blood and Marrow Transplant (BMT) and Immune Effector Cellular Therapy (IEC) program in the state.

Our experience and innovation with adult and pediatric blood and bone marrow transplantation and CAR-T cell therapy have resulted in outcomes that are among the best in the country. Our internationally recognized team of specialists and researchers have reduced associated complications, making transplantation possible for people not previously eligible.

As a pioneer in blood and bone marrow transplant and CAR-T research, we are the definitive source of hope for many adult and pediatric patients battling acute and chronic leukemia, Hodgkin lymphoma, non-Hodgkin lymphoma, multiple myeloma, and other diseases. We perform transplants for a variety of non-malignant conditions as well, including bone marrow failure syndromes, sickle cell disease, and immunodeficiencies.

According to the CIBMTR/NMDP Report published in 2023, which averaged and compared the combined years of 2019-2021, our BMT program achieved an actual one-year survival rate of 77.6% for patients receiving first allogeneic transplants. This rate is above the national average of 76.2%. We are also transplanting almost twice the percentage of minority patients than the national network, which speaks to our mission of providing access and breaking down barriers.

Living Donor Program

The Blood and Marrow Transplant team offers access to transplants through living blood and bone marrow donation.

Why our program?

We have the expertise and the caring team to get you through treatment. Our BMT program received national recognition as Press Ganey’s team of the year in 2018 for our outstanding care coordination and teamwork in pursuit of delivering safe, high-quality, compassionate care. In addition, our inpatient pediatric and adult units regularly rank in the top 1-3% in the nation in Press Ganey's patient satisfaction surveys.

Other distinctions include:

  • A designated blood and bone marrow transplant center for South Carolina's Medicaid program.
  • South Carolina's only approved umbilical cord blood transplant program.
  • South Carolina's only pediatric blood and bone marrow transplant program.
  • A National Marrow Donor Program collection and transplant center since 1993.
  • Accredited by FACT (Foundation for the Accreditation of Cellular Therapy) since 2003.


  • Celebrated our 3,000th BMT transplant (June 2024)
  • Offered the first CAR-T therapy in South Carolina (March 2019)
  • Celebrated our 2,000th BMT transplant (November 2018)
  • Launched the BMT Outpatient Program (April 2018)
  • Recognized MUSC BMT Program's 30th Anniversary (Feb. 23, 2017)
  • Performed:
    • First haploidentical transplant in South Carolina (2009)
    • First reduced intensity transplant in South Carolina (2000)
    • First cord blood transplant in South Carolina (1997)
    • The world’s first outpatient matched unrelated transplant (1996)
    • The first matched unrelated transplant in South Carolina (1993)
    • The first adult and the first pediatric bone marrow transplants in South Carolina (1987)

About Blood & Bone Marrow Transplantation

At Hollings, our Blood and Marrow Transplant team creates an individualized treatment plan that is unique to each patient's needs and provides curative therapy for a broad range of illnesses. We also offer opportunities for patients to participate in clinical trials, including several for the prevention and treatment of graft-versus-host disease.

Delivering cutting-edge care

illustration of CAR T cells attacking cancer cells

For certain blood cancer patients, Hollings offers CAR-T cell therapy, which is an innovative treatment that can be very powerful.

CAR-T Cell Therapy

Our Team

One of the strengths of the Blood and Marrow Transplant Program is the specially trained, multidisciplinary team.