Skip to main content

LOWVELO

A one-of-a-kind cycling event for riders of all ages and levels that funds lifesaving cancer research at Hollings. 

Register Now
a group of riders pass under the finish line truss at Lowvelo25 with people on either side cheering them on

LOWVELO / [ low·vel·oh ] / Noun.

A combination of the words Lowcountry and velo, the French word for “bike.” A cycling event that brings a dedicated group of riders, volunteers, virtual participants, sponsors and staff members together to raise funds for innovative and lifesaving cancer research at the state’s only National Cancer Institute-designated cancer center: MUSC Hollings Cancer Center in Charleston.

 

Overhead view of a group of bicyclists heading up the Ravenel Bridge on-ramp as the sun rises in front of them.

Join us for LOWVELO

There’s room for everyone at LOWVELO, our annual fundraising bike ride on November 7. Whether you’re interested in biking, volunteering or donating, your efforts help to advance cancer research at MUSC Hollings Cancer Center.

Ride
Donate
Volunteer
The Research
A route for everyone

Ride

Are you looking for a family-friendly ride around the islands? A vigorous ride through the beauty of Francis Marion National Forest? Or what about a music-thumping, arm-pumping stationary cycling class?

LOWVELO offers all this and more.

LOWVELO is about raising money for cancer research. But it’s also about living a healthy lifestyle and moving our bodies.

Our annual bike ride offers five routes, ranging from seven to 80 miles, and stationary rides at the finish line. There’s also a virtual Home Team option!

Let’s Ride!
A pair of smiling riders approach the Lowvelo finish line in a celebratory mood.
Funding Cancer Research

Donate

Show your support for your favorite rider or donate in honor of a loved one. When you donate to LOWVELO, rest assured that your money will stay right here in South Carolina, funding lifesaving cancer research at MUSC Hollings Cancer Center. And thanks to the generosity of our sponsors, 100% of rider-raised dollars go directly to research.

Donate Now
A large banner at the Lowvelo finish line block party filled with handwritten messages about why people ride in Lowvelo.
Your Support Makes It Happen

Volunteer

Pulling off an event like LOWVELO doesn’t happen without help! We need between 300 and 500 volunteers to ensure a smooth and successful day. Whether you’re willing to assemble packets, staff a rest station, direct parking or make sure that every rider gets a big cheer at the finish line, we appreciate your time and talent! 

Volunteer
A smiling group of volunteers cheer and wave pom poms.
Changing What’s Possible

The Research

Since the first ride in 2019, riders have raised $4.6 million for cancer research. This money has funded projects for researchers using CAR-Tregs against cancer, looking for better ways to address depression in cancer survivors, exploring more effective treatment options for triple negative breast cancer, and much more. 

Impact
a graduate student wearing headphones works in a research lab

 Extraordinary Impact

LOWVELO rallies everyone together for one great cause — raising money for innovative and lifesaving cancer research at MUSC Hollings Cancer Center. And thanks to the generosity of our sponsors, 100% of rider-raised dollars go directly to research.

1,640 people participated in 2025.
$1.1M raised in 2025, a new milestone.
$4.6M raised since LOWVELO began in 2019.
$24M in full-scale NIH grants secured from LOWVELO seed funding.
Learn More
a large group stands together on the bridge over Breach Inlet with their bikes off to the side during a break in their Lowvelo ride
a large group of cyclists rides past a historic church with a tall white steeple in downtown Charleston during the Lowvelo bike ride
a woman and small boy ride down the Lowvelo finish line chute with another group of riders behind them
a large group of riders stand in front of a Lowvelo backdrop cheering and raising their arms in the air
a group of Lowvelo25 cyclists rides past the MUSC Hollings Cancer Center building, which uses the money raised during the event for research
a woman writes a message on a large fabric sign intended for people to share why they ride in the Lowvelo fundraising bike ride
Stationary cyclists under a tent wave towels overhead.
a large group of cyclists ride over a bridge with beach houses behind them
a large group of cyclists ride under the Lowvelo25 starting line truss

LOWVELO Stories

See More Stories
A group of cyclists wave as they ride on a city street.
What is LOWVELO?
A large happy family of multiple generations.
Riding for a beloved father and grandfather
A woman in a bike helmet stands holding her bike.
A second chance for Sylvie Baele
Freezing fog wafts as a researcher lifts samples out of a container of liquid nitrogen in a research lab.
How LOWVELO is funding big ideas by Dr. Leo Ferreira

I love the fact that we are able to cycle and pedal to raise dollars for cancer research and really make a difference in cancer care.

Dr. Denis Guttridge Hollings researcher