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Gynecologic Cancer Expertise

Gynecologic cancer is a term that covers all types of cancer in the female reproductive system. This includes cervical cancer, ovarian cancer, uterine cancer (often called endometrial cancer), vaginal cancer and vulvar cancer. More than 1,100 women a year entrust their gynecologic cancer care to the multi-disciplinary team at MUSC Hollings Cancer Center.

At Hollings, our gynecologic cancer team is led by gynecologic oncologists. These specialists are doctors who trained for four years as OB/GYNs and then pursued additional training to focus on cancer diagnosis and treatment. In addition to these specialists, our team includes radiation oncologists, gynecologic pathologists, advanced practice nurses who focus on women’s cancers, a nurse navigator dedicated to gynecologic cancer patients, social workers, a dietitian focused on cancer patients’ unique needs, psychological support services and more. Our primary concern is ensuring you are treated with compassion and thoroughness.

National recognition in gynecologic cancer surgery

MUSC Hollings Cancer Center has been recognized as High Performing in Gynecologic Cancer Surgery in the 2025–2026 U.S. News & World Report rankings. This honor highlights our team's skill in executing complex gynecologic procedures with excellent outcomes.

The Hollings difference

Gynecologic cancer treatment

At Hollings, our gynecologic cancer specialists understand that your situation is unique and that you deserve a specially tailored plan based on your needs.

Our treatment options include:

Minimally invasive surgery

Our team is trained in the use of laparoscopic surgery and the da Vinci Surgical System, a robot that helps to increase surgical precision. These techniques are used for:

  • Early pelvic mass evaluations.
  • Staging and treatment for early endometrial, ovarian and cervical cancer.
  • Robotic-assisted laparoscopic lymph node assessment.

If surgery will be a part of your treatment plan, check out our Gynecology Oncology Surgery Guide to get a better understanding of what to expect and how to prepare.

Radiation therapy

  • Specialized radiation oncology services to target therapy and decrease side effects.
  • Intensity-modulated radiation therapy (IMRT) in addition to traditional external beam radiation.
  • Vaginal brachytherapy for treatment of endometrial cancers.

Gynecologic cancer clinical trials

As a National Cancer Institute-designated cancer center, we firmly believe that clinical trials are an important part of cancer care. Clinical trials show us whether new treatments work better than existing treatments. That’s important for future patients. But clinical trials are also important for current patients, because they offer the possibility of early access to new therapies or protocols that could become the standard-of-care in the future.

We offer a variety of gynecologic cancer clinical trials, including trials developed by researchers here at Hollings, industry trials and trials organized by other cancer centers. Learn more about clinical trials at Hollings and see our current gynecologic cancer, cervical cancer, ovarian cancer and uterine cancer clinical trials.

Hollings is also a partner in the GOG Foundation, a collaborative network of more than 400 sites across the country doing gynecologic cancer clinical and translational research, and a member of NRG Oncology, a cooperative group that organizes multi-institution cancer clinical trials. Through membership in these groups, Hollings is able to offer a wider variety of clinical trials. Ask your doctor if there is a clinical trial that fits your individual needs.

Refer a gynecologic cancer patient

To refer a gynecologic cancer patient to Hollings, please call patient referral coordinator Morgan Krohn (843-985-0580). If you are a referring provider, please submit our GYN Oncology Referral Form.

Nurse navigator support

You and your doctor will discuss the pros and cons of each option and decide on the best course of treatment for you. Our gynecologic cancer nurse navigators, Brooke Winkler, MSN, RN, at our Charleston area locations and Antonio Rivera, BSN, RN, OCN, at Tidelands, will help you understand what to expect during treatment and answer questions you may have.

Gynecologic cancer care providers

Accepting New Patients
Brian Orr

Brian Orr, MD, MS

4.9/5.0 - 307 rating
Specialties
  • Gynecologic Cancer
Locations (2)
  • Charleston, SC
  • Okatie, SC
Accepting New Patients
Whitney S Graybill

Whitney S Graybill, MD, MS

4.8/5.0 - 158 rating
Specialties
  • Gynecologic Cancer
Locations (2)
  • Charleston, SC
  • Mount Pleasant, SC
Taylor Orellana

Taylor Orellana, MD

4.9/5.0 - 61 rating
Specialties
  • Gynecologic Cancer
Locations (1)
  • Charleston, SC
Justin Harold

Justin Harold, MD

4.9/5.0 - 170 rating
Specialties
  • Gynecologic Cancer
Locations (2)
  • Charleston, SC
  • Murrells Inlet, SC
Accepting New Patients
David Mysona

David Mysona, MD

Specialties
  • Gynecologic Cancer
Locations (2)
  • Charleston, SC
  • Okatie, SC
Accepting New Patients
Samuel L Cooper

Samuel L Cooper, MD

4.9/5.0 - 136 rating
Specialties
  • Radiation Oncology
  • Blood & Lymphatic Cancer
Locations (2)
  • Charleston, SC
  • Mount Pleasant, SC

More than 14,000 women in the U.S. are expected to be diagnosed with cervical cancer — but it is one of the types of cancer that can be prevented with the HPV vaccine, which is available at Hollings. We also offer you options for early diagnosis and staging of all types of gynecologic cancers, including:

  • Human papillomavirus testing in addition to Pap smear.
  • Colposcopic assessment for cervical pre-invasive and invasive disease.
  • Same-day in-clinic fine needle aspiration as indicated.
  • Positron Emission Tomography (PET/CT Scan) as indicated.
  • Interventional radiology for image-guided biopsy.
  • Robotic surgery.

Our team of researchers and doctors are making new discoveries of more targeted and effective treatment for gynecologic cancer. Areas our researchers are focusing on include:

In addition, Hollings’ Gynecologic Oncology Transdisciplinary Cancer Team brings together expertise from different disciplines in basic and clinical research to collaborate on ongoing gynecologic cancer research.

Gynecologic Cancer Care Locations

MUSC Health Gynecology Oncology at Tidelands Health

Address
4040 Hwy 17 Bypass
Suite 306
Murrells Inlet, SC 29576
Specialties
  • Gynecologic Cancer

MUSC Health Nexton Medical Center

Address
Nexton Medical Center
1850 Nexton Parkway
Summerville, SC 29486
Specialties
  • Biliary Cancer
  • Blood & Lymphatic Cancer

MUSC Health Gynecology Oncology at East Cooper Medical Pavilion

Address
1280 Hospital Drive
Mount Pleasant, SC 29464
Hours
Specialties
  • Gynecologic Cancer

MUSC Women's Health at Hollings Cancer Center

Address
86 Jonathan Lucas St
2nd Floor
Charleston, SC 29425
Hours
Specialties
  • Gynecologic Cancer

The one thing that Dr. Orr said that stuck out to me the most was he wanted to keep me on a curative path. It was the best thing he could have said to me because it gave me that hope right off the bat that he's got me.

Common questions about gynecologic cancer

Your doctor can answer questions specific to your care, but we have compiled a list of some of the most common questions for your reference below.

All gynecologic oncologists have first trained as obstetrician-gynecologists (OB/GYNs) during a four-year residency program. After residency, they get additional training in gynecologic cancers. At MUSC, our gynecologic oncology fellows spend 12 months on a research project and 24 months on clinical care. This specialized training means that gynecologic oncologists have expertise in the female reproductive system as well as insight into the emotions that a reproductive system cancer can provoke.

Your primary care doctor or gynecologist may have referred you because a biopsy confirmed cancer. Or, your doctor may have referred you because the diagnosis isn’t clear and a specialist is needed to determine your exact diagnosis. If you have questions, ask your referring doctor or your gynecologic oncologist.

We recommend that anyone with a gynecologic cancer be treated by a gynecologic oncologist. These specialists have expertise in the female reproductive system and cancer. They perform surgery and oversee medical treatments like chemotherapy and immunotherapy.

The most common gynecologic cancer is uterine cancer – specifically, endometrial cancer, or cancer of the lining of the uterus. It is also one of the top 10 most common cancers overall. The rates of new cases of endometrial cancer and of deaths from endometrial cancer have been steadily increasing.

Latest gynecologic cancer news