Pre-Clinical and Clinical Concepts Award Application

Full applications are due by 5 p.m. on Monday, March 9, 2020. Please send a single PDF file to Brett Bechtol (bechtolb@musc.edu).

Application Instructions

Application Format

Use standard 11-point font, single space, and half-inch margins throughout the application. Consecutively number all pages.

Face Page

Complete attached Face Page form.

Abstract

200-word limit.

Prior Internal Funding History

  • Mandatory; half-page limit
  • Answer “Yes” or “No” to the question: “Have you ever received Hollings Cancer Center pilot project funding before?”

  • If “Yes”:

  1. State the internal funding mechanism(s), project(s) and period of execution dates.
  2. List any IITs that were facilitated by the pilot award.

  3. List (including the dates) extramural application(s) submitted and extramural grants awarded that were derived from the pilot award.

Response to Prior Critiques

For resubmissions only; one-page limit.

Specific Aims

State concisely the hypothesis to be tested and the specific aim(s) to be achieved during the one-year project period (one-page limit).

Research Strategy

  • Background-Significance-Innovation (one-page limit)

  • Approach (three-page limit)

Future Funding Plans

State the corporations, agencies, mechanisms, and timing of planned future grant applications that will utilize the preliminary data produced under this award. State how data from this application will be used to support extramural proposals (mandatory; 200-word limit).

Budget

Use PHS 398 form page four followed by a budget justification. Budget cap is $50,000 in direct costs. There are no indirect costs allowed. No faculty salaries, student tuition and fees, or equipment should be included. Faculty effort related to this award must be listed. Salary or stipend support for laboratory personnel, RAs, postdoctoral fellows, study coordinators, etc. may be included. Every budgeted item must be classified into a category (e.g., supplies, patient care costs, etc.). Travel expenses will only be allowed when necessary to carry out the proposed research project.

Literature Cited

List only references pertinent to the proposed research. References do not count against the page limit.

Biosketches

NIH-format biosketches for all faculty team investigators must be included. Personal statements must include the specific role of the team member.

In addition to the standard NIH-format biosketch sections (which include current and recent research support), include an additional pending support section that lists all pending grant applications. Describe any overlap or relationship between the pending application and this Pre-Clinical & Clinical Concepts application. Give the expected notification date for each pending application.

Letters of Support

Letters of support from the appropriate individuals, which may include your Hollings Cancer Center Program Leader, collaborator(s), and/or mentor (if pertinent), are required and should be sent in confidentiality to Brett Bechtol (bechtolb@musc.edu).

Junior Faculty

Please include a one-page mentoring plan with your application.

Awardee Expectations

  • Publication or presentation of results in a national forum.
  • Development of an investigator-initiated clinical trial.

  • Acceptance of LOI and extramural support for a clinical trial.