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Advanced Genomics Profiling Pricing

MUSC Hollings Cancer Center members will receive a 25% subsidy on all pricing during invoicing.

The prices listed are subject to adjustment by the shared resource at any time, and the shared resource has the right to interpret these prices.

The shared resource has the right to not accept samples if they do not pass QC.

Bulk Nucleic Acid Sequencing (Full service: Library + Sequencing)

AGP Service Price/Sample
Bulk mRNA-seq $175
ChIP-seq/Cut & RUN  $185
Ultra-low input mRNA-seq $205
Ultra-low input total RNA-seq  $205
Ultra-low input sRNA-seq  $205
Small RNA-seq  $195
Total RNA-seq  $205

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Bulk Nucleic Acid Sequencing (Library Only)

AGP Service Price/Sample 
ATAC-seq Library Only  $200
Whole-exome sequencing (100x coverage, 15Gb raw data output) Library Only $200 (Sample processing fee of $30/sample will be added.)
Whole genome sequencing (30x coverage, 100Gb raw data output) Library Only $200 (Sample processing fee of $30/sample will be added.) 

Note: For sequencing depth and pricing, please contact majumder@musc.edu.

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Single-Cell Sequencing (Library + Sequencing)

AGP Service Approx. Cell Recovery/Sample
(depends on submission)
 Read Pairs/Cell  Price/Sample 
10X single-cell gene expression 20,000 30,000-40,000 $2,700
PIPseq from Illumina Inquire Inquire Inquire
10X single-cell gene expression+ scRNA-seq with feature barcode  20,000 30,000-40,000/7,500-10,000 $3,250
scRNA-seq+CRISPR Inquire Inquire Inquire
10X On-Chip Multiplexing (4-plex)  20,000/4-plex 30,000-40,000 $3,500 (4-plex)*
10X scRNA Immune/5’ scRNA-seq 20,000 30,000-40,000 $2,700
10X scRNA Immune/5’ scRNA-seq (GEX +TCR or BCR) 20,000 30,000-40,000/7,500-10,000 $3,250
10X scRNA Immune/5’ scRNA-seq (GEX +TCR +BCR)  20,000 30,000-40,000/7,500-10,000 $3,900
Flex scRNA-seq (sc/snRNA-seq using fixed cells 4-, 16-, or n-plex) 20,000 ~20,000 (Illumina, Paired reads) $1,500
Flex scRNA-seq (sc/snRNAseq using fixed cells 4-, 16-, or n-plex) 20,000 ~30,000 (UG100, reads) # $1,350
Epi ATAC 10,000 50,000 $2,800
Multiome (snATAC-seq +snRNA-seq) 20,000 45,000/35,000 ( ATAC/GEX)  $4,500

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Single-Cell Sequencing (Library only)

AGP Service Approx. Cell Recovery/Sample
(depends on submission)
Read Pairs/Cell Price/Sample  
Intraseq (single or multiplex) Library Only  20,000 Inquire $2,750

Note: If you need more than double the recommended minimum reads (included in the service cost), please contact majumder@musc.edu. There will be extra charges added to the service. 


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Spatial Transcriptomics (Library only)

Visium HD Assays

AGP Service Price/Section 
Visium HD CytAssist (spatial transcriptomics, 6.5mm) 2 sections/slide $4,000
Visium HD CytAssist (spatial transcriptomics, 11mm)  Inquire

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Xenium Service

Fees cover all work performed by AGP, which begins once we receive the Xenium slide with the tissue sections on it. Fees are billed on a per-slide basis. Assays (User provides all 10X Genomics Kits).

AGP Service Price/Slide 
Sample handling fee and Xenium Runs (2 slides/run) $1,250 ($2,500/run) 

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Nanostring nCounter

Transcriptomics: $600/codeset (12-samples) for hybridization, running, and data delivery (differential expression).

Multiomic Assay: $1,400/codeset (12 samples for protein followed by the same 12 samples for RNA) for protein hybridization, photocleaving, RNA hybridization, running, and data delivery.

Note: All kits are purchased by the user. Kits should be sent directly to AGP to avoid multiple freeze-thaws. Please see Infinity for details or consult with majumder@musc.edu

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Other Services

AGP Service Academic (Price/Sample) 
Nanodrop 8 Spectrophotometer $1
Droplet Digital PCR (ddPCR)  $70/8 samples
Quantus nucleic acid quantification $3.50
TapeStation Regular $8.50
TapeStation High Sensitivity $11
TapeStation gDNA  $12
Automated DNA/RNA extraction  $45
RNA cleanup $10

shRNA

Item Price Format Note
Individual shRNA clones (glycerol)
$50/clone
Live culture stock
1-2ml culture will be provided;
Antibiotics: 75ug/ml Carbenicillin

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Instruments (Unsupervised)

Please reserve the following services through Infinity.

Item Price/Hour 
Miltenyi Tissue Dissociator 
$25
Miltenyi Tissue Dissociator
$35 (cold pack)
Covaris Ultrasonicator
$25
Speedvac 
$0

For sequencing depth and charges, please consult with majumder@musc.edu. The prices of scRNA-seq depend on the targeted cell number and the sequencing depth.