Translational Science Lab

gloved hand reaches out toward a transparent touch screen showing a brain and dna strand

The mission of the Translational Science Laboratory (TSL) is to facilitate the translation of basic science research to the clinical setting and vice versa with the intention of improving diagnosis and treatment strategies for cancer patients. The primary goals of the TSL are to:

  • Develop and validate a portfolio of novel biomarker assays that are available for translational studies.
  • Provide education to faculty and staff regarding novel technologies.
  • Provide project management for studies that utilize resources available through other shared resources, investigator laboratories, and outside vendors.
  • Initiate collaborations and form strategic partnerships between Hollings clinical investigators and pharmaceutical corporations.

The TSL works closely with clinical and translational scientists to drive the development and utilization of novel biomarker assays to provide the most innovative pre-clinical and correlative science studies associated with early phase oncology clinical trials.

Staff

Director

Jian Ouyang headshot

Jian Ouyang, Ph.D.

ouyangj@musc.edu

Mrinmoyee Majumder headshot 

Director of Operations

Mrinmoyee Majumder, Ph.D.
majumder@musc.edu

Senior Scientist

Silvia Vaena, Ph.D.
vaena@musc.edu

Services and Expertise

  • Automated Purification of DNA, RNA, miRNA from cells, blood, FFPE, or fresh frozen tissue samples.
  • Custom targeted cancer NGS library generation.Single-Cell Sequencing (10X Genomics).
  • Droplet digital PCR (BioRad QX200).
  • The RNAi Consortium’s (TRC) genome-wide lentivirus-based mouse and human shRNA libraries.
  • In situ hybridization.
  • Protein purification and Enzyme-Linked Immunosorbent Assays (ELISA).
  • Data analysis.