Expert care with a personal touch

Our vulvar and vaginal cancer doctors know what you're going through and will support you every step of the way.

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a smiling woman in a white doctor's coat talks with another woman

Vulvar and Vaginal Cancer

As an NCI-designated cancer center, Hollings is equipped to treat rare cancers that are less familiar to most doctors, including cancer in the vulva or vagina. These gynecologic cancers account for only 6% - 8% of all female reproductive system cancers.

Our multidisciplinary teams are led by gynecologic oncologists — doctors who specialize in cancers in the female reproductive system — and include radiation oncologists, gynecologic pathologists, advanced practice nurses who focus on women’s cancers, a nurse navigator dedicated to gynecologic cancer patients, social workers, a dietitian focused on cancer patients’ unique needs, psychological support services and more. Our team is committed to helping you to have the best outcome possible. 

High Performing Hospital | University Medical Center | US News & World Report 2024-2025 | Gynecological Cancer Surgery

In good hands

You know you're in good hands at MUSC Hollings Cancer Center, the state’s only National Cancer Institute-designated cancer center. Here, you have access to the latest innovations in cancer treatment, including clinical trials, advanced surgical techniques, support services and survivorship planning. You can rest easy knowing we hold national rankings for cancer care and take a leadership role in cancer research and prevention.

The Hollings difference

Vulvar and vaginal cancer symptoms

Vulvar and vaginal cancer might not cause symptoms at first. Speak to your health care provider if you experience the following:

  • Unusual bleeding
  • Bleeding after intercourse
  • Pain in the pelvis
  • Skin changes, including lumps, sores, change in color or rash
  • Itching, burning or tenderness

Referrals and support

Refer a vulvar or vaginal cancer patient

To refer a vulvar or vaginal cancer patient to Hollings, please call patient referral coordinators Ulani DeCillis (843-985-0579) or Morgan Krohn (843-985-0580). If you are a referring provider, please submit our GYN Oncology Referral Form.

Nurse navigator support

You and your doctor will discuss the pros and cons of each option and decide on the best course of treatment for you. Our gynecologic cancer nurse navigators, Lorri Bennett, RN, MSN, CCRC, at our Charleston area locations and Antonio Rivera, BSN, RN, OCN, at Tidelands, will help you understand what to expect during treatment and answer questions you may have.

Our experienced gynecologic cancer care team will complete a thorough review of your cancer and create a personalized treatment plan.

Dr. Katie Schmitt guides a patient doing a physical therapy exercise with a metal bar

Support from start to finish

We pride ourselves on our holistic approach to cancer care. We offer you many resources to help you throughout your cancer journey, including financial counseling, physical therapy, nutrition services, and support groups.

Patient Resources

Gynecologic Cancer Care Locations

MUSC Hollings Cancer Center Downtown

86 Jonathan Lucas Street

Charleston, SC 29425

Scheduling: 843-792-9300

Gynecology Oncology Beaufort

122 Okatie Center Boulevard North

Okatie, SC 29909

Gynecology Oncology East Cooper

East Cooper Medical Pavilion

1280 Hospital Drive

Mount Pleasant, SC 29464

Gynecology Oncology Florence

805 Pamplico Highway

Suite: 320

Florence, SC 29505

Scheduling: 843-792-9300

Gynecology Oncology Murrells Inlet

Waccamaw Medical Park West

4040 Hwy 17 Bypass

Suite: 306

Murrells Inlet, SC 29576

Scheduling: 843-792-9300

Hollings Cancer Center Orangeburg

1161 Cook Road

Orangeburg, SC 29118

Vulvar and vaginal cancer risk factors

Infection with human papillomavirus (HPV) is a risk factor for developing vulvar or vaginal cancer. HPV is a common virus that will infect most people at some point. Most of the time, the infection clears up. But in some cases, high-risk forms of HPV will stick around and eventually cause cancer. HPV infection can cause six types of cancer: cervical, penile, vaginal, vulvar, anal and oropharyngeal (throat) cancer.

There is a vaccine against HPV that can protect against developing these cancers. The HPV vaccine is recommended for both boys and girls at ages 11 and 12, and people can get catchup vaccines through age 26. People between the ages of 27 and 45 can talk to their doctors about whether to get the vaccine.

Other risk factors for vulvar and vaginal cancers include:

  • Have had vaginal, vulvar or cervical precancer
  • Have had cervical cancer
  • Being immunocompromised
rendering of the human papillomavirus

Protect yourself from HPV

The HPV vaccine can prevent six types of cancer in both men and women, including vulvar and vaginal cancer. The HPV vaccine is typically given to children, but people up to the age of 45 may be eligible. Talk with your doctor for more information.

HPV vaccination