Vulvar and Vaginal Cancer

As an NCI-designated cancer center, Hollings is equipped to treat rare cancers that are less familiar to most doctors, including cancer in the vulva or vagina. These gynecologic cancers account for only 6% - 8% of all female reproductive system cancers.

Our multidisciplinary teams are led by gynecologic oncologists — doctors who specialize in cancers in the female reproductive system — and include radiation oncologists, gynecologic pathologists, advanced practice nurses who focus on women’s cancers, a nurse navigator dedicated to gynecologic cancer patients, social workers, a dietitian focused on cancer patients’ unique needs, psychological support services and more. Our team is committed to helping you to have the best outcome possible. 

Symptoms | Referrals and Support | Care Locations | Risk Factors

Vulvar and vaginal cancer symptoms

Vulvar and vaginal cancer might not cause symptoms at first. Speak to your health care provider if you experience the following:

• Unusual bleeding
• Bleeding after intercourse
• Pain in the pelvis
• Skin changes, including lumps, sores, change in color or rash
• Itching, burning or tenderness

Referrals and support

Refer a vulvar or vaginal cancer patient

To refer a vulvar or vaginal cancer patient to Hollings, please call patient referral coordinators Ulani DeCillis (843-985-0579) or Morgan Krohn (843-985-0580). If you are a referring provider, please submit our GYN Oncology Referral Form.

Nurse navigator support

You and your doctor will discuss the pros and cons of each option and decide on the best course of treatment for you. Our gynecologic cancer nurse navigator, Lorri Bennett, RN, MSN, CCRC, will help you understand what to expect during treatment and answer questions you may have.

Vulvar and vaginal cancer risk factors

Infection with human papillomavirus (HPV) is a risk factor for developing vulvar or vaginal cancer. HPV is a common virus that will infect most people at some point. Most of the time, the infection clears up. But in some cases, high-risk forms of HPV will stick around and eventually cause cancer. HPV infection can cause six types of cancer: cervical, penile, vaginal, vulvar, anal and oropharyngeal (throat) cancer.

There is a vaccine against HPV that can protect against developing these cancers. The HPV vaccine is recommended for both boys and girls at ages 11 and 12, and people can get catchup vaccines through age 26. People between the ages of 27 and 45 can talk to their doctors about whether to get the vaccine.

Other risk factors for vulvar and vaginal cancers include:

• Have had vaginal, vulvar or cervical precancer
• Have had cervical cancer
• Being immunocompromised