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MUSC Hollings Cancer Center is one of a small number of health care centers in the U.S. offering you focused sarcoma care. Our team includes fellowship-trained clinicians in orthopaedic oncology, surgical oncology and medical oncology, all with a clinical focus on sarcoma patients.

There are about 15,000 new cases of sarcoma diagnosed across the country each year. Since this cancer is so rare, it is important that you’re treated at a center with a team of doctors experienced in this disease. Our program also has experienced pathology and musculoskeletal radiology experts for proper diagnosis, which is crucial for effective treatment.

We’re Here For You

At Hollings, we know a cancer diagnosis can be a life changing event. We are here to support you through your journey. Call 843-792-9300 and make an appointment. Experience what sets us apart.

National recognition in cancer care

MUSC Hollings Cancer Center has been recognized as High Performing in Cancer Care in the 2025–2026 U.S. News & World Report rankings. This honor underscores our advanced expertise and dedication to providing patients with innovative treatments and personalized care.

Treatment and Support

The Hollings team of experts uses state-of-the-art technology to provide you with an accurate diagnosis and the best care possible. At Hollings, we treat many different types of sarcoma including:

Bone Sarcoma

  • Osteosarcoma
  • Ewing’s sarcoma
  • Chondrosarcoma
  • Pleomorphic undifferentiated sarcoma of the bone

Soft Tissue Sarcoma

  • Pleomorphic undifferentiated sarcoma
  • Synovial sarcoma
  • Liposarcoma
  • Fibrosarcoma
  • Myxofibrosarcoma
  • Dermatofibrosarcoma protuberans (DFSP)
  • Leiomyosarcoma
  • Angiosarcoma
  • Lymph angiosarcoma

  • Epithelioid sarcoma
  • Desmoid
  • Atypical lipomatous tumor
  • Gastrointestinal stromal tumor (GIST)
  • Rhabdomyosarcoma
  • Clear cell sarcoma
  • Myxoid sarcoma
  • Alveolar sarcoma
  • Solitary Fibrous tumor

Our team of sarcoma specialists knows how important it is to offer you options when it comes to your treatment. Some of the resources available to you include:

Advanced Imaging

MRI, PET and CT scans allow for accurate interpretation, which aids surgical and radiation planning.

Surgical Treatment

Our surgeons are not only experienced in the removal of sarcomas, but also in how best to reconstruct the tissue or skeletal defect, maximizing your post-operative function. Procedures include biopsy of primary tumors, removal of primary tumors, limb-sparing surgery and surgical treatment of metastatic disease.

Systemic Therapies

Our experts guide the selection of appropriate post-surgical therapy and manage systemic therapy options specific to your sarcoma subtype including bone, soft tissue sarcomas and non-gastrointestinal stromal tumors.

Pathology

Our pathologists take advantage of advancements in cancer genetics and technology using genetic markers to aid in diagnosis and prognosis.

Medical Management

Personalized tumor staging, chemotherapy and radiation plans are developed by a multidisciplinary team experienced in sarcoma.

Refer a sarcoma patient

To refer a sarcoma patient to Hollings, please call patient referral coordinator Paula Pearson at 843-985-0584.

Nurse Navigator Support

Our sarcoma nurse navigator, Melinda Walto, BSN, RN, will help you understand what to expect during treatment and answer questions you may have.

Although they are rare, it is important to catch sarcomas early. You should advise your doctor about any unexplained lumps or growths, which could be signs of soft tissue sarcoma. At Hollings, our team utilizes expertise in the field and imaging like X-rays, ultrasounds and CT scans to provide you an accurate and detailed diagnosis.

Because sarcomas are rare, there are still many questions health professionals are seeking answers for. At Hollings, we understand how important research is in understanding sarcoma and developing effective treatments.

Some recent projects include:

As South Carolina’s only NCI-designated cancer center, Hollings offers you clinical trials and treatments that aren’t available anywhere else in the state. These opportunities provide you with access to the latest medications, therapies, and surgical techniques that can improve your outcomes. Learn more about clinical trials at Hollings and see our current sarcoma clinical trials.

What am I going to do today to fight this damned disease? What email am I going to send? Who am I going to go encourage? How can I get somebody to donate $1? What did I do today? I've tried every day to do something.

Sarcoma Care Locations

MUSC Health Orthopaedics at Hollings Cancer Center

Address
86 Jonathan Lucas St
Charleston, SC 29425
Get Directions
Hours
Specialties
  • Orthopaedics
  • Orthopaedics - Foot & Ankle

MUSC Health Hematology Oncology at East Cooper Medical Pavilion

Address
1600 Midtown Ave
3rd Floor
Mount Pleasant, SC 29464
Get Directions
Hours
Specialties
  • Benign Hematology
  • Bone Marrow Transplant Program

MUSC Health Infusion Services at Nexton Medical Park

Address
Nexton Medical Park
5500 Front Street
Suite 140
Summerville, SC 29486
Get Directions
Hours
Specialties
  • Antibiotics
  • Benign Hematology

Find a Provider

MUSC Health has a doctor or provider for you. Search by location, keyword, or specialty.

Accepting New Patients
Lee Leddy

Lee Leddy, MD, MSCR

4.9/5.0 - 208 rating
Specialties
  • Sarcoma Cancer
  • Orthopaedics
Locations (3)
  • Charleston, SC
  • Okatie, SC
  • West Columbia, SC
Accepting New Patients
Jennifer Harper

Jennifer Harper, MD

4.9/5.0 - 233 rating
Specialties
  • Breast Cancer
  • Head & Neck Cancer
Locations (2)
  • Charleston, SC
  • Mount Pleasant, SC
Accepting New Patients
Andrea Abbott

Andrea Abbott, MD, MSCR

4.9/5.0 - 68 rating
Specialties
  • Sarcoma Cancer
  • Breast Cancer
Locations (3)
  • Charleston, SC
  • Mount Pleasant, SC
  • North Charleston, SC

He made a promise to his niece. Michael Mansson was going to ride 100 miles in LOWVELO and nothing was going to stop him.

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