Research News at Hollings

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Clinical trial of purified CAR-T cell therapy awarded $3.2M NCI grant to expand

a group of people stand in a hospital hallway chatting

With the first two patients in a clinical trial testing purified CAR-T cells both showing complete remission, the National Cancer Institute has stepped forward with $3.2 million in funding to expand the trial.

Brian Hess, M.D., and Shikhar Mehrotra, Ph.D., have partnered on the trial, which is testing a new patented variation of CAR-T cell therapy that the researchers hope will have longer-lasting results with fewer side effects.

Learn about the trial

 

T cells attacking cancer cells. Image by Meletios Verras. Licensed from istockphoto.com

Improving Cancer Immunotherapy

Hollings researchers use patented technology to improve immunotherapy by prolonging survival of cancer-fighting T-cells.
surgical staff are bathed in blue light in the operating room

Precision Surgery

Head and neck cancer surgeons at Hollings are testing a fluorescent dye that illuminates nerves, which should make them easier to find during surgery.

a man and woman stand in a hallway of glass walls and doors

Relative Risks

Is there a role for e-cigarettes among adults who have not been able to stop using combustible cigarettes after using FDA-approved medication?
a man in a corol-colored short sleeved button down poses in a hallway lined with cabinets of supplies

Ewing Sarcoma

An Ewing sarcoma researcher at MUSC is one of three scientists nationwide to receive a career development award from the Rally Foundation.
tobacco researcher Kinsey Pebley poses in a garden

Smoking Cessation Aid

An MUSC Hollings Cancer Center fellow was awarded a national grant to pursue her idea: making short helpful videos for cancer patients trying to stop smoking.

HPV public health researcher Kalyani "Kelly" Sonawane

Vaccine Hesitation

The parents of millions of teens don't intend to vaccinate them against HPV, a virus that can cause six types of cancer.

closeup of vials of HPV vaccine with a needle

HPV Vaccination

Researchers find stagnant HPV vaccine rates among young adults, though LGBTQ vaccination rates are a bright spot.

three researchers in white lab coats pose in the Sahin breast cancer research lab

Overcoming Drug Resistance

Breast cancer often develops resistance to previously effective drugs. Hollings researchers showed how the effectiveness of one drug might be restored.

a doctor casually leans on a hospital bed in upright position to chat with the patient sitting in it

CAR-T Clinical Trial

CAR-T-cell therapy can be a powerful treatment for blood cancers, but it also has significant side effects. A clinical trial at Hollings seeks to change that.