ACS IRG Application Guidelines

Notifications of intent to submit are due on Friday, March 11, 2022 by 4 p.m. and full applications are due on Friday, April 15, 2022, by 4 p.m.

Application Checklist

American Cancer Society Institutional Research Grant 2022 RFA

If you are submitting a renewal application, you must include a progress report. The form can be found attached at the end of the RFA linked above. Please do not exceed the two-page limit for the progress report. If you are resubmitting an application (you may resubmit up to two times), you must include a one-page document detailing your responses to the critiques from the previous application. Note: This only applies to resubmitted applications, not projects being submitted for the first time.

  • Application Format: Use standard 11-point Arial font, single space, and half-inch margins throughout the application. Consecutively number all pages.
  • Face Page: Complete the Face Page form that can be found attached at the end of the RFA linked above.
  • Table of Contents: Provide page number for each category listed in the Table of Contents. Number pages consecutively at the bottom of each page throughout the application.
  • Detailed Budget: Use Budget Form attached to the RFA linked above to complete the 12-month budget. Budget cap is $35,000, direct costs. Include direct costs only; there are no indirect costs associated with this grant. No faculty salaries should be included; however the appropriate amount of effort you and your collaborators will contribute to this project should be indicated. Principal Investigators must attribute at least 5% effort to this project. Please follow these guidelines as you prepare your budget:


    Expenditures Allowed

    • Research supplies and animal maintenance
    • Technical assistance
    • Domestic travel when necessary to carry out the proposed research program
    • Publication costs, including reprints
    • Costs of computer time
    • Special fees (pathology, photography, etc.)
    • Stipends for graduate students and postdoctoral assistants if their role is to promote and sustain the project presented by the junior faculty member
    • Equipment costing less than $2,000 (special justification is necessary for items exceeding this amount)
    • Registration fees at scientific meetings

    Expenditures Not Allowed

    • Secretarial/administrative personnel
    • Salary of principal investigator
    • Tuition
    • Foreign travel (special consideration will be given for attendance at scientific meetings held in Canada)
    • Honoraria and travel expenses for visiting lecturers
    • Per Diem charges for hospital beds
    • Non-medical services to patients (travel to a clinical site or patient incentives are allowable expenses)
    • Construction, renovation, or building/laboratory maintenance
    • Purchasing and binding of periodicals and books
    • Office and laboratory furniture
    • Office equipment and supplies
    • Rental of office or laboratory space
    • Recruiting and relocation expenses
    • Dues and membership fees in scientific societies
  • Budget Justification: On a separate page, clearly justify each item requested in the budget. Describe mentors and collaborators and their roles on the project.
  • Biographical Sketch: Use NIH Biosketch. Include any present or recently completed research support. Include biosketches of collaborators and mentors. Guidelines can be found on the NIH website.
  • Facilities and Resources: Using form attached on the RFA linked above, describe resources and facilities available to support proposed research.
  • Letters of Support: Research Assistant Professors must include a letter of support from their Department Chair or Division Director confirming their independent research status. In addition, all applicants must include a letter of support from their Chairperson and primary mentors indicating their endorsement of the proposed research and their commitment to mentoring the applicant through the award year. If the applicant’s research is thematically similar to that of his or her primary mentor, the mentor must clarify the distinction between the mentor’s research and the applicant’s proposal.
  • Research Plan: The research plan should include sufficient information needed for evaluation of the project, independent of any other document. No appendices allowed. (6 pages maximum plus an additional 300 [or fewer] words to describe statistical considerations.)
    • Specific Aims: List the broad, long-term objectives and what the specific research proposed in this application is intended to accomplish. State the hypotheses to be tested.
    • Background and Significance: Briefly sketch the background leading to the present application; critically evaluate existing knowledge, and specifically identify the gaps which the project is intended to fill. State concisely the importance and health relevance of the research described in the application by relating the specific aims to the broad long-term objectives.
    • Preliminary Studies: For new applications, use this section to provide an account of the principal investigator’s preliminary studies pertinent to the application information that will help establish the experience and competence of the investigator to pursue the proposed project.
    • Research Design and Methods: Describe how you will do the research. Describe the research design and the procedures to be used to accomplish the specific aims of the project.  Include how the data will be collected, analyzed, and interpreted. Describe any new methodology and its advantage over existing methodologies. Discuss potential difficulties and limitations of the proposed procedures and alternative approaches to achieve the aims. Provide a tentative sequence or timetable for the project. Point out any procedures, situations, or materials that may be hazardous to personnel and the precautions to be exercised.
    • Statistical Considerations: Describe how the data will be analyzed and used to make inferences regarding the Specific Aims. A justification of sample size should be included for animal studies and any aims that include human tissue samples, patients, or healthy volunteers. An additional 300 words (approximately a half page) is allowed for this section beyond the 6-page limit. If more than 300 words are needed, the statistical considerations section can extend into the 6-page proposal.
    • Literature Cited (not included in the page limitation): List all references. Each reference must include the title, names of all authors, book or journal, volume number, page numbers, and year of publication. The reference should be limited to relevant and current literature. Select only those references pertinent to the proposed research.